THC-O is also considered a prodrug. This means that the psychoactive effects will not be noticed until the chemical substance has been transformed after use. Traditional edibles are the most durable dosing style available. The THC-O effect of traditional edibles can generally be expected to last between 4 and 8 hours.
However, sublingual edibles can decrease more quickly, usually within 4 to 6 hours. Maybe THC-O is different from any of those cannabinoids?.