The absolute minimum amount you need to take to notice the effects of THC-O is 0.5 mg, or approximately two or three 5-second injections of disposable THC-O. Following the example of dosing other psychedelics, such as psilocybin, “magic mushrooms” or even LSD, their dose can make your psychedelic experience a success or a failure. THC-O takes about 1 hour if ingested in gummies or tinctures. If it takes longer, do not take more than 2 hours after your last dose.
Ingesting cannabinoids takes a while, but the effects are more powerful and last longer than when vaping or smoking. Buy only products from trusted manufacturers with an impeccable safety record. Be careful when dosing THC-O by following the adage of starting small and going slowly. While not much is known about the effects of THC-O, those who use this cannabinoid believe that it can help relieve pain, increase appetite and reduce anxiety.
Consumers also report the following side effects. Anecdotal reports also suggest that THC-O users experience a mild psychedelic high that is both spiritual and introspective. Jordan Tishler MD, a leading expert in cannabis therapies at InhaleMD, and Kelly McLoughlin, executive director of FlowerChild CBD, to learn more about THC-O and find answers to these questions. As always, the best way to dose THC-O is to try a little and then keep increasing until you feel what you need.
In short, THC-O has the effects of a mild psychedelic, but it takes much longer to affect the body than other types of THC. Dosing with THC-O acetate tinctures requires that you divide the amount of milligrams of THC-O in the bottle by the amount of milliliters it contains. THC-O vape cartridges, like all inhalable products, act very quickly and are more powerful due to the bioavailability of this type of THC-O product and the method of administration. Research on this topic is still very new, but it seems that THC-O has a higher bioavailability than other forms of THC.
Each gummy in a pack will contain the same amount of milligrams of THC-O, which means that to adjust the dose you take, you just have to change the amount of gummy you consume with each serving. Over time, the safety profile of THC-O could change as industry experts work on creating safe THC-O formulations. Whether cannabis is a psychedelic has long been debated and, for those curious about psychedelics, THC-O may represent an attractive starting point. The legal gray area surrounding delta-8 THC is clearing up, leaving THC-O ready to take its place in the hemp by-product market.
Obviously, the amount of THC-O-acetate you take in a single session has the biggest influence on how you feel. There is no data on whether THC-O is fully metabolized in the liver when taken orally or if it can accumulate (causing toxicity). While there is still no proof that THC-O can cause the same harm as vitamin E acetate, gummies or tinctures may represent a safer bet than vape carts until more is known. However, with the most powerful variants, such as THC-O, experts like Tishler and Russo are concerned about the possibility of harm related to an overdose.
Since THC-O acetate and THC-O products are so potent, it's natural that hemp enthusiasts of all levels of experience want to be a little more conscious when it comes to dosing.